dichroism and cell imaging will be discussed. Methods for the separation and study of biological macromolecules
and membranes including utracentrifugation, chromatography, electrophoresis, mass spectometry and calorimetry
will be introduced.
521 / BIOPHYS 521 Techniques in Biophysical Chemistry. (3 hrs.) Prereq. 430, 461 or BIOLCHEM 415. This
course is team-taught and is the second of a two-term biophysical Chemistry series, BIOPHYS 520/521, but it can
be taken as a stand-alone course. BIOPHYS 521 provides an overview of the theory and application of
spectroscopical techniques of UV/Vis, IR, Fluorescence, Single Molecule Detection, CD, and NMR. Other topics
covered include X-ray crystallography, computational methods, light scattering, ultracentrifugation. When possible,
hands-on opportunities in applying some of these techniques will be offered.
525 / CHEMBIO 525 Chemical Biology I. (3hrs.) Exploration of the application of chemical principles to biology.
Together with CHEM 526, this constitutes a comprehensive one year introduction to the field of chemical biology.
526 / CHEMBIO 526 Chemical Biology II. (3hrs.) Exploration of the application of chemical principles to
biology. Together with CHEM 525, this constitutes a comprehensive one year introduction to the field of chemical
biology.
528 / BIOLCHEM 528 / MEDCHEM 528 Biology and Chemistry of Enzymes. (2 hrs.) Prereq. 501 or
BIOLCHEM 550. This course will explore the roles of organic and organometallic cofactors in biology. Topics
covered will be cofactor assembly, cofactors as sensors, and cofactors in enzyme Chemistry, with an emphasis on
modulation of cofactor reactivity by complexation with the protein. The lectures will be complemented by assigned
reading material from the primary literature and will assume basic familiarity with bioorganic Chemistry.
536 / MACROMOL 536. Laboratory in Macromolecular Chemistry. (3 hrs.) Prereq. 535 or Phys
418/permission. Experimental methods for the study of macromolecular materials in solution and in bulk state.
538 Organic Chemistry of Macromolecules. (3 hrs.) The preparation, reactions, and properties of high
molecular weight polymeric materials of both natural and synthetic origin.
540 Organic Principles. (3 hrs.) Mechanisms of organic chemical reactions, stereochemistry, and conformational
analysis. The important types of organic reactions are discussed. Basic principles are emphasized; relatively little
attention is paid to the scope and synthetic applications of the reactions.
541 Advanced Organic Chemistry. (3 hrs.) Prereq. 540. Synthetic Organic Chemistry. The scope and limitations
of the more important synthetic reactions are discussed within the framework of multi-step organic synthesis.
542 Application of Physical Methods to Organic Chemistry. (3 hrs.) Applications of infrared, ultraviolet,
nuclear magnetic resonance spectroscopy, optical rotatory dispersion/circular dichroism spectroscopy, mass
spectrometry and other physical methods to the study and identification of the structure and reactions of organic
compounds.
543 Organic Mechanisms. (3 hrs.) Students will learn to propose and write reasonable mechanisms for organic
reactions, including complex multi-step processes. Knowledge of the details of the fundamental organic reaction
processes will also be gained.
548 New Frontiers at the Chemistry/Biology Interface. (1 hr.) Students attend seminars that describe topics at
the frontiers of Chemistry and Biology.
550 / EDUC 550 Chemistry Education. (3 hrs.) Chemistry Education Research and Practice. This course will
prepare future secondary and post-secondary chemistry educators to translate chemistry education research into
effective classroom practice. Students will read and critically evaluate literature from top Chemistry Education and
Science Education Journals. Students will learn about, prepare, and test their own formative and summative
assessments. Students will practice student-centered classroom techniques and reflect on and develop their own
teaching identity and style. Students will learn about issues of diversity and equity and learn strategies to foster
inclusivity in the science classroom.
551 / BIOINF 551 / BIOLCHEM 551 / BIOMEDE 551 / PATH 551 Proteome Informatics. (3 hrs.)
Introduction to proteomics, mass spectrometry, peptide identification and protein inference, statistical methods and
computational algorithms, post-translational modifications, genome annotation and alternative splicing,
quantitative proteomics and differential protein expression analysis, protein-protein interaction networks and
protein complexes, data mining and analysis of large-scale data sets, clinical applications, related technologies such
a metabolomics and protein arrays, data integration and systems biology.
567 / AOSS 567. Chemical Dynamics. (3 hrs.) Prereq.461 or AOSS 479. Chemical Kinetics is the study of the
rates and mechanisms of systems undergoing chemical change. The extraction of rate data from reacting systems
and the utilization of such data in other reacting systems is central to Chemistry in the laboratory and in the